.box {
  width: 100px;
  height: 100px;
  animation-name: move;
  animation-duration: 5s;
  animation-timing-function: ease-in-out;
}
@keyframes move {
  0% {
    background-color: red;
    transform: translate(0px);
  }
  25% {
    background-color: blue;
    transform: translate(0px, 250px);
  }
  50% {
    background-color: green;
    transform: translate(250px, 250px);
  }
  75% {
    background-color: yellow;
    transform: translate(250px, 0px);
  }
  100% {
    background-color: red;
    transform: translate(0px);
  }
}